Turn the page of any catalog and the first thing you look at is the upper left hand corner of the spread. Thats where to place your best seller, your bread and butter, right?
Well, what if your best seller is a visual dog? What if, for instance, your mainstay is black shoes? Kill the rule, raise another flag.
Put a pair of wild socks in the upper left for stopping power and direct your reader to the old tried and true elsewhere on the spread.