Both of these words describe substances that cause injury, illness, or death when they get into your body.
The difference is that poison gets into your body if you inhale it (breathe it in), ingest it (eat or drink), or touch it. Venom gets into your body if it is injected in, such as through a bite or a sting.
Certain snakes are venomous, because they bite you and inject their venom (although many native English speakers say "poisonous snake"). Scorpions and some spiders are also venomous, because they bite or sting you. There are plants and frogs that are poisonous - you will get sick if you touch them or eat them.
Sometimes people use poison to kill other people - by secretly putting it into their food or drink. When this happens, we say the victim was poisoned.
The biggest killers on the road are fatigue and alcohol. Before you depart you should quickly research a rough plan of your route including the driving times and distances. If you will be stopping to sightsee en route you should plan a maximum of four hours of driving in a day. If you have a long distance driving day you should plan to have a non-driving day afterwards to recover. Make sure you do not drink alcohol and drive.Allow an extra day or two so you can be flexible if you decide to stay longer in a place or decide to break a longer drive into two shorter driving days, or if something unexpected occurs. Also do some initial research into sightseeing options along the way so you know where you are interested to visit and can build these into your plan.Online tools such as Google Maps enable you to quickly put together a route plan.