1. Despite indicates an illogical occurrence.
We had a good time despite the bad weather.
2. In spite of has the same meaning and usage as despite.
We had a good time in spite of the bad weather.
Diseases and hearing loss
Hearing loss can be caused by viral diseases including mumps, measles, pertussis (whooping cough) and rubella (German measles). These types of infections are more common in childhood, although adults who havent been immunised and didnt have the diseases in childhood may catch them too.Bacterial diseases, such as meningitis and syphilis, can also target and harm the ears. A tumour which grows on the hearing nerve, called an