Required for carbohydrate metabolism, adrenal function, enzyme reactions, and production of fats, cholesterol, bile acids, hormones, neurotransmitters, and red blood cells.
Deficiency is rare, except in malnutrition, and causes burning/tingling in hands and feet, fatigue, and headache.
Drugs that deplete vitamin B5: oral contraceptives, amitriptyline, imipramine, and desipramine.
Most people get adequate niacin from diet and/or a multivitamin.